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Professor

    Shigehiko Kanaya   Ph.D.    



Research Interests
  • Metabolome informatics
  • Proteome informatics
  • Transcriptome informatics
  • Comparative genomics



    • Education
    B.Sc. degree in Bio-science from Science University of Tokyo, Japan in 1985,
    Ph.D. from Toyohashi University of Technology, Japan in 1990,




    Professonal Experience
    Assistant Professor in Information Engineering at Yamagata Univ. in 1990,
    Guest Associate Professor at National Institute of Genetics in 1996,
    Associate Professor at Electronic and Information Engineering in 1999,
    Associate Professor, Applied Biosystem Engineering at Yamagata Univ. in 2000,
    Guest researcher at BioradicalInstitute (Yamagata Prefecture), in 2000
    Associate Professor, Research and Education Center for Genetic Information at NAIST in 2001,
    Associate Professor, Graduate School of Information Science at NAIST in 2002,
    Professor, Graduate School of Information Science at NAIST in 2004-.



    Publications (~2000)
    1. S. Kanaya, Y. Ujiie, K. Hasegawa, T. Sato, H. Imada, M. Kinouchi, Y. Kudo, T. Ogata, H. Ohya, H. Kamada, K. Itamoto, K. Katsura, Proteome analysis of Oncorhynchus species during embryogenesis, Electrophoresis, 21, 1907-1913 (2000)
    2. M. Kinouchi, S. Kanaya, Y. Kudo, Detection of transfer RNA based on the cloverleaf secondary structure, J. Comput. Aided Chem., 1, 76-81 (2000)
    3. Y. Ujiie, K. Sasaki, M. Kinouchi, Y. Kudo, S. Kanaya, Prediction of proteolytic process based on N-terminal sequences and molecular weights by proteomics and proteome analysis, J. Comput. Aided Chem., 1, 82-88 (2000)
    4. M. Ohno, T. Tenzen, Y. Watanabe, T. Yamagata, S. Kanaya, T. Ikemura, Non-B DNA structures spatially and sequence-specifically associated with individual centromeres in the human interphase nucleus, Chromosomes Today, 13, 57-69 (2000)
    5. K. Nakayama, K. Takashima, H. Ishihara, T. Shinomiya, M. Kageyama, S. Kanaya, M. Ohnishi, T. Murata, H. Mori, T. Hayashi, The R-type pyocin of Pseudomonas aeruginosa is related to P2 phage, and the F-type is related to lambda phage, Mol. Microbiol., 38, 213-231 (2000)
    6. K. Nakayama, S. Kanaya, M. Ohnishi, Y. Terawaki, T. Hayashi, The complete nucleotide sequence of ?CTX, a cytotoxin-converting phage of Pseudomonas aeruginosa: implications for phage evolution and horizontal gene transfer via bacgteriophages, Mol. Microbiol., 31, 399-419 (1999)
    7. S. Kanaya, Y. Yamada, Y. Kudo, T. Ikemura, Studies of codon usage and tRNA genes of 18 unicellular organisms and quantification of Bacillus subtilis tRNAs: gene expression level and species-specific diversity of codon usage based on multivariate analysis, Gene, 238, 143-155 (1999)
    8. T. Kunisawa, S. Kanaya, E. Kutter, Comparison of synonymous codon distribution patterns of bacteriophage and host genomes, DNA Res., 5, 319-326 (1998)
    9. S. Kanaya, T. Okumura, H. Fukasawa, M. Miyauchi, Y. Kudo, Assessment of protein coding sequences in Bacillus subtilis genome using species-specific diversity of genes in codon usage based on multivariate analysis: comparison of the diversity between B. subtilis and Escherichia coli, Res. Commun. in Biochem. and Cell & Mol. Biology, 1, 82-92 (1997)
    10. S. Kanaya, Y. Kudo, K. Nakamura, T. Ikemura, Detection of genes in Escherichia coli sequences determined by genome projects and prediction of protein production levels, based on multivariate diversity in codon usage, CABIOS(Bioinformatics), 12, 213-225 (1996)
    11. Y. Nakamura, K. Wada, Y. Wada, H. Doi, S. Kanaya, T. Gojobori, T. Ikemura, Codon usage tabulated from the international DNA sequence databases, Nucleic Acids Res., 24, 214-215 (1996)
    12. S. Kanaya, Y. Kudo, S. Moki-Toda, K. Katsura, C. Del Carpio, Synchronous gene expressions during embryogenesis of Oncorhynchus masou (YAMAME), Biochem. and Mol. Biol. International, 39, 261-266 (1996)
    13. S. Kanaya, Y. Kudo, Genome propensities of Escherichia coli and elevencoliphages for under- and overabundance of ?70-consensus-like sequences, Int. J. Genome Res., 1, 261-277 (1994)
    14. S. Kanaya, Y. Kudo, Statistical examination of dissimilarity of promoter and promoter-like sequences in Eshcherichia coli, Anal. Sci., 7, 739-742 (1991)
    15. H. Abe, S. Kanaya, T. Komukai, Y. Takahashi, and S. Sasaki, Systematization of semantic descriptions of odors, Anal. Chim. Acta, 239, 73-85 (1990)
    16. H. Abe, S. Kanaya, Y. Takahashi, S. Sasaki, combined semiconductor gas sensor system for detection of specific substances in particular environments, Anal. Chim. Acta, 219, 213-222 (1989)
    17. Y. Miyashita, S. Kanaya, H. Katsumi, C. Takayama, A., Nagakura, and S. Sasaki, Structure-taste correlation of substituted beta-(3-hydroxy-4- Methoxypheynyl) ethylbenzenes using pattern recognition method, Chem. Senses, 14, 781-792 (1989)
    18. H. Abe, S. Kanaya, Y. Takahashi, and S. Sasaki, Method for monitoring sensor stability in a multiple semiconductor gas-sensor system, Anal. Chim. Acta, 225, 89-96 (1989)
    19. T. Okuyama, Y. Miyashita, S. Kanaya, H. Katsumi, S. Sasaki, M. Randic, Computer assisted structure-taste studies on sulfamates by pattern recognition method using graph theoretical invariants, J. Comput. Chem., 9, 636-646 (1988)
    20. H. Abe, S. Kanaya, T. Takahashi, S. Sasaki, Extended studies of the automated odor-sensing system based on plural semiconductor gas sensors with computerized pattern recognition techniques, Anal. Chim. Acta, 215, 155-168 (1988)
    21. H. Abe, T. Yoshimura, S. Kanaya, Y. Takahashi, Y. Miyashita, S. Sasaki, Automated odor-sensing system based on plural semiconductor gas sensors and computerized pattern recognition, Anal. Chim. Acta, 194, 1-9 (1987)





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